Turbulence & Rheology, Dr. D. Penney


WHY HEMOGLOBIN IS PACKAGED IN ERYTHROCYTES

  • gives non-Newtonian characteristics to blood (i.e. Fahraeus-Lindqvist effect)

  • adds little to the osmotic pressure of the plasma

  • prevents loss of the respiratory pigment from the body via the kidneys, seepage into the lymphatics, intercellular space, etc.

  • allows use of a Hb of relatively small m.w. and size. Provides high oxygen carrying capacity.

  • provides enhanced control of oxygen affinity (e.g. 2,3 - DPG) (i.e. Hb in solu., would need much higher B.P. to maintain equilibrium



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