O2 Uptake, Exercise & Cor. Circ., Dr. D. Penney


Coronary Oxygen Delivery Determinants:

  • Coronary blood flow - resistance, pressure (duration), cardiac output

  • Hemoglobin - amount, kind

  • HbO2 dissociation curve

  • Cardiac myoglobin

  • Capillary - myocyte distance (10-13 um)

  • Capillary density ( 1 : 1 )

  • RBC deformability, rheology (e.g. sickle cell)



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