Developmental Pathophysiology, Develop. Physiol., Dr. D. Penney

Table 4.04a. Some Maternal Problems that Increase Morbidity / Mortality.

Multiple pregnancy
Preterm labor
Placento previa
Placental abruption
Postpartum hemorrhage

Cardiac disease (1% of pregnant women)
CAD (coronary artery disease)
CHF (congestive heart failure) -->
Acute pulmonary edema
Mitral stenosis (rheumatic fever)
Mitral regurgitation
Mitral valve prolapse
L --> R shunts - ASD, VSD, PDA
R --> L shunts - Eisenmenger's syndrome (progressive pulm. hypertension)
....... Tetralogy of Fallot
....... Pulm. artery hypertension

Marfan syndrome (autosomal dom. disorder of connective tissue)

Hypertension (7-13% of pregnancies)

....... chronic Htn., pre-eclampsia-eclampsia, etc.

Pre-eclampsia - Htn., HELLP syndrome (Hemolysis, Liver Enzymes, Low Platelet count)

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