Developmental Pathophysiology, Develop. Physiol., Dr. D. Penney



Figure 4.12 - Elevated ventricular output in the neonate results in decreased reserve (capacity) under conditions of volume loading. When fetal, newborn and older sheep were given rapid saline infusions to produce a maximal increase in ventricular output, output rose by about 35% during the first postnatal week, while the increase to a comparable volume load in older animals was much greater.


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