Page 23, Developmental Pathophysiology, Develop. Physiol., Dr. D. Penney



Congenital Defects (cont...)

Coarctation of the aorta:

Obstruction due to concentric narrowing of the distal aortic arch, usually occurs just beyond the left subclavian artery (Table 4.22.) This produces a pressure gradient between the ascending and descending aorta. Compensatory enlargement of the chest wall arteries allows flow around the obstructed region.

Increasing hypertension in the central area takes place with age, imposing severe afterload on the left ventricle with resultant enlargement. Increasing blood pressure and pulse are detected in the upper body, with an absence or diminished pulse in the legs.


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