Early Development, Devel. Physiol., Dr. D. Penney
Table 2.01 - Early Heart Development:
Cardiac Primordium:
- Arises from cardiogenic plate (splanchnic mesoderm) lying in front of head, beneath pericardial chamber
- Head (neural plate) grows forward, reversing orientation, to below foregut, above pericardial coelom
- Caudal end continuous with mesoderm; receives veins there
Cardiac Tube:
- Two longitudinal strands of mesodermal cells, each forming cavities
- Thin-walled endothelial tubes within splanchnic mesoderm; begin fusing first at cranial end into a single tube
- Internal endothelial tissue becomes future endothelium lining; external, thick covering gives rise to myocardium and epicardium
- Heart tube suspended by dorsal mesocardium; later disappears.
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